International Journal of Stem Cells : eISSN 2005-5447

Table. 1.

Table. 1.

Characteristics of included studies

StudyCountry of Pts’ enrollmentDiseaseNBaseline LVEF (Mean)Route of deliveryMSC originCell originCell dose (×106)Measurement toolMSC differentiationF/U (mo)RoB


TxCoTxCo
Ascheim (2014)USACMI201017.519.3IMBMAllo25EchoYes3High
Bartolucci (2017)ChileCMI151532.629.6IVUCAllo1MRINo12Low
Bartunek (2013)Belgium, Serbia, SwitzerlandCMI321527.527.8IMBMAuto2EchoYes6Low
Chen (2004)ChinaAMI353449.048.0ICBMAuto5SPECTNo6High
Chen (2006)ChinaCMI222326.023.0ICBMAuto3.1SPECTNo12High
Chullikana (2015)IndiaAMI101043.143.4IVBMAllo4EchoNo6Low
Gao (2013)ChinaAMI212250.851.4ICBMAuto2EchoNo6High
Gao (2015)ChinaAMI585852.051.1ICWJAuto6SPECTNo18High
Hare (2009)USAAMI392147.345.1IVBMAllo1MRINo6Low
Heldman (2014)USACMI191135.728.1IMBMAllo1.5MRINo12Low
Lee (2014)KoreaAMI333649.052.3ICBMAuto72SPECTNo6High
Mathiasen (2015)DenmarkCMI402028.225.1IMBMAuto2~3*MRINo6Low
Perin (2015)USACMI451531.334.6IMBMAllo25~150EchoYes12Low
Teerlink (2017)Hungary, Poland, Belgium, Israel, Italy, Spain, Switzerland, Bulgaria, SerbiaCMI12015127.028.0IMBMAuto600EchoYes12Low

unit=ml;

unit=mol/L;

Tx: treatment, Co: control, LVEF: left ventricular ejection fraction, AMI: acute myocardial infarction, CMI: chronic myocardial infarction, IC: intracoronary, IV: intravenous, IM: intramyocardial, Echo: echocardiography, SPECT: single-photon emission computed tomography, MRI: magnetic resonance imaging, FU: follow-up, BM: bone marrow, WJ: Wharton’s jelly, Auto: autologous, Allo: allogeneic, RoB: risk of bias, Low: low risk of bias, High: high risk of bias.

International Journal of Stem Cells 2018;11:1-12 https://doi.org/10.15283/ijsc17061
© 2018 International Journal of Stem Cells