International Journal of Stem Cells : eISSN 2005-5447

Fig. 1.

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Fig. 1. Survival and distribution of Olig2-GFP-hMSCs in spinal cord lesion after contusive SCI. (A) Green fluorescent protein (GFP) and Olig2 expression in genetically modified hMSCs. The GFP-infected (GFP-hMSCs) and Olig2-GFP-infected (Olig2-GFP-hMSCs) hMSCs were immunostained with an anti-Olig2 (red) antibody. Colocalization of Oilg2 and GFP in the nucleus of Olig2-GFP-hMSCs is shown in the merged image (yellow). Scale bars: 100 μm. (B) Schematic diagram of the experimental design. (C) Immunohistochemistry of transplanted hMSCs in spinal cord lesion at 7 weeks after transplantation. Longitudinal spinal cord sections were immunostained for GFP at 7 weeks after transplantation of GFP-hMSCs and Olig2-GFP-hMSCs. Scale bars: 500 μm. The left side is rostral and the superior side is dorsal.
International Journal of Stem Cells 2018;11:177-86
© 2018 International Journal of Stem Cells