International Journal of Stem Cells : eISSN 2005-5447

Fig. 4.

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Fig. 4. The inhibition of ERK5 by XMD-8-92 regulates on cell cycle- and apoptosis-related genes in AML cells. (A, B) The protein (A) and mRNA (B) levels of c-Myc decreased in Kasumi-1 cells through the inhibition of ERK5. (C and D) Analysis of the cell cycle- and apoptosis-related genes in Kasumi-1 (C) and HL-60 (D) cells by qRT-PCR. Relative expression of genes was calculated relative to GAPDH. Data represent mean±SD of 3 independent experiments. *p<0.05, **p<0.01, ***p<0.005 indicates a significant difference between samples.
International Journal of Stem Cells 2018;11:227-34 https://doi.org/10.15283/ijsc18053
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