International Journal of Stem Cells : eISSN 2005-5447

Fig. 4.

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Fig. 4. Differentiation potential of the long-term expanded hepatic organoids. (A) Schematic diagram of organoid differentiation for further hepatic maturation. Hepatic medium (HM); Expansion medium (EM); and Differentiation medium (DM). (B) mRNA expression levels of ALB, RBP4, and CYP3A4 in HM- or DM-cultured organoids at passage 10. (C) Representative morphology and (D) mRNA expression levels of ALB, RBP4, and CYP3A4 of differentiated hepatic organoids at each indicated passage. Data are the mean±SEM (n=3) and analyzed by Student’s t-test. *p<0.05; **p<0.01; and ***p<0.001.
International Journal of Stem Cells 2020;13:279-86 https://doi.org/10.15283/ijsc20060
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