Fig. 2. LPA in the nervous system. (A) In neural progenitor cells, LPA promotes the survival of neural progenitor cells, as well as an increase in terminal mitosis. (B) In neurons, LPA changes to cell morphology and promotes growth cone collapse. (C) In oligodendrocytes, LPA promotes maturation and myelination. (D) In astrocytes, LPA activates the proliferation of astrocytes.