International Journal of Stem Cells : eISSN 2005-5447

Fig. 6.

Download original image
Fig. 6. HucMSC-ex-Galectin-3 promoted the transformation of fibroblasts to an anti-inflammatory phe-notype. Cardiac fibroblasts were treated with LPS (100 ng/ml), LPS+hucMSC-ex (200 μg/ml), LPS+hucMSC-NC-ex (200 μg/ml), or LPS+hucMSC-si-ex (200 μg/ml) for 24 h. (A, B) IL-1β, TNF-α, and TGF-β protein levels were detected by western blot. (C∼E) The mRNA expression of IL-1β, TNF-α, and TGF-β were detected by qRT-PCR. (F) Two days after myocardial infarction was induced, IL-1β, TNF-α, and TGF-β expression in the infarcted area were detected by immunohistochemistry. Scale bar= 20 μm. *p<0.05, **p<0.01, and ***p<0.001.
International Journal of Stem Cells 2021;14:320-30
© 2021 International Journal of Stem Cells