International Journal of Stem Cells : eISSN 2005-5447

Fig. 1.

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Fig. 1. Irisin-treated BMSCs rescued the cardiac function in MI mouse in vivo. (a) Representative images of echocardiography showing the improved cardiac function in BMSCs treated with irisin. (b) The ejection fraction (EF) and fractional shortening (FS) are gradually recovered in the BMSCs+irisin group when compared with other groups (n=8 for Sham, 5 for DMEM, 6 for BMSCs+irisin and BMSCs+Con). (c) The infarct area was examined by Sirius Red staining 28 days post-MI (n=6 for every group). (d) The infarct size in hearts was quantified using Image-Pro. All data were measured as mean±standard error of the mean (SEM). *p<0.05. BMSCs, bone marrow mesenchymal stem cells; MI, myocardial infarction; DMEM, Dulbecco’s Modified Eagle Medium.
International Journal of Stem Cells 2021;14:455-64
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