International Journal of Stem Cells : eISSN 2005-5447

Fig. 6.

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Fig. 6. Inhibition of RA signaling pathway by BMS biases the differentiation of hiPSC to Sinoatrial node-like cells. BMS at 5 μM was introduced on day 5 after the differentiation, and the expression of COUPTFII, cTNT/SHOX2, and cTNT/NKX2.5 was evaluated by flow cytometry. Representative FACS plots showing that inhibition of RA signaling pathway by BMS decreases the percentage of COUPTFII positive cardiomyocytes (A) and increases the percentage of SHOX2/cTNT (B) and cTNT/NKX2.5 (C) cardio-myocytes.
International Journal of Stem Cells 2022;15:247-57 https://doi.org/10.15283/ijsc21148
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