Fig. 5. hUC-MSCs rescued the expression of p-VEGFR2 and p-AKT in emphysema induced by SU5416. The protein expressions of p-VEGFR2, VEGFR2, p-AKT and AKT in the lungs were determined by western blotting. Compared with the control group (CON), p-VEGFR2 and p-AKT in the model group (SU) were significantly reduced, but both of them in the hUC-MSCs transplantation group (SU＋MSC) returned to the level of the Control group. There was no significant change in the expression of VEGFR2 and AKT in each group.

International Journal of Stem Cells 2022;15:395-404 https://doi.org/10.15283/ijsc21149

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