Fig. 2. Efficacy of hBMSC in CKD rat model according to injection route and hBMSC dose. BUN: blood urea nitrogen, Ccr: Creatinine clearance, RA-C: renal artery control, RA-LD: renal artery low dose, RA-MD: renal artery moderate dose, RA-HD: renal artery high dose, TV-C: tail vein control, TV-LD: tail vein low dose, TV-MD: tail vein moderate dose, TV-HD: tail vein high dose. *p<0.05; **p<0.01; ***p<0.001, vs. the RA-C group; *p<0.05; **p<0.01; ***p<0.001, vs. the TV-C group; Red colored stars indicate statistically significant differences in RA-LD, RA-MD, RA-HD, groups compared to the RA-C group, respectively. Blue colored stars indicate statistically significant differences in TV-LD, TV-MD, TV-HD, groups compared to the TV-C group, respectively. (A∼H) 3 times per rat, 10 rats per group, but 9 rats in the RA-C, TV-LD, TV-HD groups and 8 rats in the TV-MD groups.

International Journal of Stem Cells 2023;16:66-77 https://doi.org/10.15283/ijsc21146

© 2022 International Journal of Stem Cells