Fig. 4. Histopathological analysis of the tail vein injection group. (A) Histopathological scoring, cortex. (B) Histopathological scoring, medulla. (C) Sirius red, cortex. (D) Sirius red, medulla. (E) TUNEL, cortex. (F) TUNEL, medulla. (G) α-SMA, cortex. (H) α-SMA, medulla. (I) ED-1, cortex. (J) ED-1, medulla. Non-overlapping fields (400×). NS, p>0.05; *p<0.05; **p<0.01; ***p<0.001 vs. the TV-C group; ^$$p<0.01, vs. the TV-LD group; TV-C: tail vein control, TV-LD: tail vein low dose, TV-MD: tail vein moderate dose, TV-HD: tail vein high dose. (A, B) 10 fields per rat, 10 rats per group, but 9 rats in the RA-C, TV-LD, TV-HD groups and 8 rats in the TV-MD groups. (C∼J) 4 fields per rat, 10 rats per group, but 9 rats in the RA-C, TV-LD, TV-HD groups and 8 rats in the TV-MD groups.

International Journal of Stem Cells 2023;16:66-77 https://doi.org/10.15283/ijsc21146

© 2022 International Journal of Stem Cells