Fig. 2. Effect of S0859 on prolifera-tion and intracellular pH of DPSCs. (A) A CCK-8 assay revealed that low S0859 concentration had little effect on DPSCs viability, and a high dose inhibited proliferation (*p<0.05). (B) Standard curve for pH and its effect on DPSCs obtained using BCECF-AM. The pH/fluorescence ratio (530/640) conforms to the linear regression equation y=0.1897x＋5.9766 (R²= 0.9903). (C) Effect of S0859 on intracellular pH of DPSCs observed using BCECF-AM. The intracellular pH of DPSCs treated with S0859 decreased compared to the control group (*p< 0.05).

International Journal of Stem Cells 2022;15:384-94 https://doi.org/10.15283/ijsc21240

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