Fig. 5. Protein-protein network interaction between mature osteoblasts and BMMSCs. (A) Mature osteoblasts cluster and BMMSC1 cluster were marked in oval and hexagon, respectively. (B) Subnets of FZD1, WIF1 and SFRP4. (C) Violin plots demonstrated the expression of FZD1, WIF1, and sFRP4 in each osteogenesis cluster. ns: not significant, *p-adjusted ≤0.05, ****p-adjusted ≤0.001. (D) Schematic representation of SFRP4 and WIF1 involved in the WNT signaling pathway.

International Journal of Stem Cells 2023;16:342-55 https://doi.org/10.15283/ijsc22101

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