Fig. 4. PTHrP increases cAMP concentration and promotes PKA activation. After the transfection, cells were treated with 50 nM/ml rPTHrP for 3 days. The control group just contained the same volume of the medium. The concentration of cAMP (A∼C) and the PKA (D∼F) activity were measured by immunoassay and ELISA, respectively. The value represents the mean±standard deviation of five independent experiments (n=5). *p<0.05, **p<0.01 versus siNC group; ^###p<0.001 versus siPTHrP group.

International Journal of Stem Cells 2023;16:315-25 https://doi.org/10.15283/ijsc22097

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