International Journal of Stem Cells : eISSN 2005-5447

Fig. 2.

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Fig. 2. Biophysical cues in the MSC microenvironment for enhancing immunomodulatory function. The application of a cell culture platform that mimics the microenvironment of the MSC niche, such as spheroid formation, scaffold, stiffness, and functionalization of the substrate surface, plays an important role in strengthening cellular immunomodulation function by secreting various immuno-modulatory cytokines (IDO-1, PGE2, HO-1, COX-2, TSG-6).
International Journal of Stem Cells 2023;16:251-9 https://doi.org/10.15283/ijsc22211
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