Fig. 5. 3D-WJ-CM cream recovery in psoriasis-like mice. (A) H&E staining of mice skin by group. Scale bar=50 μm. (B) Levels of inflammatory cytokines (TLR7, IL-17α, IL-23α, IL-22, and IL-36) in the back skin of psoriasis-like mice treated with 3D-WJ-CM. IMQ: imiquimod, MTX: methotrexate, 2D: two-dimensional, WJ: Wharton’s jelly, CM: conditioned media, 3D: three-dimensional. Results with a p-value<0.05 were considered statistically significant. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001, and ns=not significant compared to the IMQ＋vehicle group.