Fig. 6. 3D-WJ-CM attenuates inflammation in vitro. (A) The concentration of nitric oxide in the supernatant of LPS-stimulated RAW 264.7 cells. (B) Protein expression levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α). Protein expression was detected in the cell supernatant by ELISA. LPS: lipopolysaccharide, MTX: methotrexate, 2D: two-dimensional, WJ: Wharton’s jelly, CM: conditioned media, 3D: three-dimensional. ***p<0.001, ****p<0.0001 compared to the LPS group.